The Phactr4 Polyclonal Antibody (PACO5093) is a valuable tool for researchers studying Phactr4, a protein involved in various cellular processes including cell migration, proliferation, and differentiation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the Phactr4 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cellular biology and cancer research.
Phactr4 is a key player in regulating cell functions such as cell adhesion and morphology, making it a promising target for exploring mechanisms underlying cancer progression and metastasis. Understanding the role of Phactr4 in these processes is crucial for developing targeted therapies and diagnostic tools for cancer and other diseases. The Phactr4 Polyclonal Antibody offers researchers a reliable tool for uncovering the functions and potential therapeutic applications of this important protein.
Antibody Name:
PHACTR4 Antibody (PACO05093)
Antibody SKU:
PACO05093
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IHC:1:200-1:1000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from the Internal region of human PHACTR4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
PHACTR4; Phosphatase and actin regulator 4
UniProt Protein Function:
PHACTR4: a protein of unknown function. Contains three RPEL repeats named after four conserved amino acids it contains. Protein type: Phosphatase; Actin-bindingChromosomal Location of Human Ortholog: 1p35.3Cellular Component: lamellipodiumMolecular Function: actin binding; protein phosphatase 1 bindingBiological Process: actin cytoskeleton organization and biogenesis; enteric nervous system development; neural crest cell migration; neural tube closure; positive regulation of catalytic activity; regulation of cell cycle; Rho protein signal transduction
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
