Based on the information provided in the URL for the PHF3 Antibody (PACO01330), we can create a product description as follows:The PHF3 Polyclonal Antibody (PACO01330) is a valuable tool for researchers studying PHF3, a protein involved in various cellular processes and signaling pathways. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in applications such as immunofluorescence and immunohistochemistry.PHF3, also known as PHD finger protein 3, is known to play a role in chromatin remodeling and gene regulation, making it a key player in gene expression and cell function.
Studies have shown that PHF3 is implicated in diseases such as cancer, where dysregulation of gene expression can lead to uncontrolled cell growth and tumor formation.By using the PHF3 antibody, researchers can study the localization and expression levels of PHF3 in different cell types and tissues, providing valuable insights into its function and potential as a therapeutic target. This antibody is a valuable tool for research in genetics, epigenetics, and cancer biology, offering a deeper understanding of the molecular mechanisms underlying disease progression and potential treatment strategies.
Antibody Name:
PHF3 Antibody
Antibody SKU:
PACO01330
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human PHF3.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
PHF3; KIAA0244; PHD finger protein 3
UniProt Protein Function:
PHF3: a ubiquitous protein containing a PHD domain, TFIIS domain, and SPOC domain, all of which are characteristic of transcription factors. Expression is significantly reduced or lost in glioblastomas, glioblastoma cell lines, anaplastic astrocytomas, and astrocytomas. Two alternatively spliced isoforms have been described.Protein type: Transcription regulationChromosomal Location of Human Ortholog: 6q12Cellular Component: nucleusMolecular Function: zinc ion bindingBiological Process: transcription, DNA-dependent; multicellular organismal development
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a PHD finger-containing gene family. This gene may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
