The PHLDA1 Polyclonal Antibody (PACO02724) is a valuable tool for researchers studying PHLDA1, a protein involved in regulating cell growth, apoptosis, and tumorigenesis. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the PHLDA1 protein, this antibody allows for accurate detection and analysis of PHLDA1 expression in a variety of cell types.PHLDA1, also known as T-cell death-associated gene 51 (TDAG51), is known to play a role in the modulation of cell survival pathways and has been implicated in various diseases, including cancer. Its functions in regulating cell proliferation and apoptosis make it a promising target for research aimed at understanding the mechanisms underlying tumorigenesis and identifying potential therapeutic strategies.
By utilizing the PHLDA1 Polyclonal Antibody (PACO02724), researchers can gain valuable insights into the intricate regulatory networks involving PHLDA1 and its impact on cell behavior. This antibody is an invaluable resource for studies in cancer biology, cell signaling, and molecular mechanisms of disease, offering a reliable tool for investigating the role of PHLDA1 in various physiological and pathological processes.
Antibody Name:
PHLDA1 Antibody
Antibody SKU:
PACO02724
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human TDAG51.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
PHLDA1; PHRIP; TDAG51; Pleckstrin homology-like domain family A member 1; Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated
UniProt Protein Function:
PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.Protein type: Nucleolus; ApoptosisChromosomal Location of Human Ortholog: 12q15Cellular Component: cytosolMolecular Function: protein bindingBiological Process: G2/M transition of mitotic cell cycle
UniProt Protein Details:
NCBI Summary:
This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1. [provided by RefSeq, Jul 2008]
