The ZFP36L1 Polyclonal Antibody (CAB8809) is a valuable tool for researchers studying the zinc finger protein 36 like 1 (ZFP36L1), a key regulator of mRNA stability and inflammation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the ZFP36L1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in immunology, inflammation, and cancer research.ZFP36L1 is involved in the degradation of mRNA molecules encoding inflammatory cytokines, thereby playing a crucial role in the regulation of immune responses and inflammation.
Its dysregulation has been implicated in various diseases, including cancer and autoimmune disorders. By studying the function of ZFP36L1, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.Overall, the ZFP36L1 Polyclonal Antibody is a valuable resource for scientists exploring the role of ZFP36L1 in health and disease. Its high specificity and sensitivity make it a reliable tool for furthering our understanding of mRNA stability and immune regulation.
Product Name:
ZFP36L1 Rabbit Polyclonal Antibody
SKU:
CAB8809
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-338 of human ZFP36L1 (NP_004917.2).
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
677
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ZFP36L1 Rabbit pAb (CAB8809) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
