The PhyKPL Polyclonal Antibody (PACO05554) is specifically designed for research involving PhyKPL, a key enzyme involved in the biosynthesis of phytol, a component of the side chain of chlorophyll. This antibody is polyclonal, raised in rabbits, and is highly reactive with samples from various species, making it versatile for different research applications.PhyKPL plays a crucial role in the chlorophyll biosynthesis pathway, which is essential for photosynthesis in plants. By targeting this enzyme with the PhyKPL Polyclonal Antibody, researchers can investigate the regulation and function of PhyKPL in plants, leading to a better understanding of chlorophyll biosynthesis and photosynthetic processes.
Validated for use in Western blot applications, the PhyKPL Polyclonal Antibody enables detection and analysis of PhyKPL protein levels in plant samples. This makes it a valuable tool for studying plant physiology, metabolism, and responses to environmental cues, ultimately contributing to advancements in agriculture, biotechnology, and plant science research.
Antibody Name:
PHYKPL Antibody (PACO05554)
Antibody SKU:
PACO05554
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the C-terminal region of human AGXT2L2.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AGXT2L2: Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: EC 4.2.3.134; TransferaseChromosomal Location of Human Ortholog: 5q35.3Cellular Component: mitochondrial matrixMolecular Function: identical protein binding; lyase activity; protein binding; pyridoxal phosphate binding; transaminase activityBiological Process: collagen catabolic process; extracellular matrix disassembly; extracellular matrix organization and biogenesis; lysine catabolic processDisease: Phosphohydroxylysinuria
UniProt Protein Details:
NCBI Summary:
This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
