The PLEK Antibody (CAB6305) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit serum, exhibits high specificity and sensitivity towards human pleckstrin, making it ideal for use in Western blotting and immunohistochemistry applications.Pleckstrin is involved in a variety of cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of pleckstrin has been linked to various diseases, such as cancer and neurological disorders, highlighting the importance of studying its function and regulation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PLEK Antibody
SKU:
CAB6305
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin cytoskeleton organization; and positive regulation of supramolecular fiber organization. Located in cytoplasm and ruffle membrane.
Purification Method
Affinity purification
Gene ID
5341
RRID
AB_2766910
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PLEK Rabbit pAb (CAB6305) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
