The Pleckstrin Monoclonal Antibody (CAB20905) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for Western blot applications. By binding to Pleckstrin, this antibody allows for the detection and analysis of this important protein in a variety of cell types.Pleckstrin plays a key role in regulating cell signaling processes, including cell growth, differentiation, and migration. Dysregulation of Pleckstrin has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
Pleckstrin Monoclonal Antibody
SKU:
CAB20905
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2870
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Enables phosphatidylinositol-3,4-bisphosphate binding activity; protein homodimerization activity; and protein kinase C binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; actin cytoskeleton organization; and positive regulation of supramolecular fiber organization. Located in cytoplasm and ruffle membrane.
Purification Method
Affinity purification
Gene ID
5341
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Pleckstrin Rabbit mAb (CAB20905) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
