The PLK4 Antibody (CAB9863) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been extensively validated for use in Western blot applications. By binding to the PLK4 protein, this antibody allows for accurate detection and analysis of its expression levels in various cell types, making it an essential tool for studies in cell biology and cancer research.PLK4, also known as polo-like kinase 4, is crucial for maintaining the proper number of centrioles in cells during division, making it a potential target for therapies aimed at disrupting cancer cell growth.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PLK4 Antibody
SKU:
CAB9863
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
10733
RRID
AB_2771714
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PLK4 Rabbit pAb (CAB9863) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 15s.
