The PPIA Antibody (CAB0993) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is suitable for use in Western blot applications.PPIA is a multifunctional protein involved in protein folding and signaling pathways, making it a key player in cellular processes. Its role in immune response modulation and its association with various diseases, including cancer and viral infections, have attracted significant interest from researchers in the fields of immunology and virology.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PPIA Antibody
SKU:
CAB0993
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
MANA GPNT NGSQ FFIC TAKT EWLD GKHV VFGK VKEG MNIV EAME RFGS RNGK TSKK ITIA DCGQ LE
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:2000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CYPA, CYPH, HEL-S-69p, PPIA
Positive Sample:
K-562, Jurkat, HepG2, HeLa, NIH/3T3, Mouse lung, mouse spleen, rat spleen, mouse brain, rat brain
Cellular Localization:
Cytoplasm, Secreted.
Calculated MW:
18kDa
Observed MW:
17kDa
This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported.
Purification Method
Affinity purification
Gene ID
5478
RRID
AB_2757512
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PPIA Rabbit pAb (CAB0993) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
