The PPM1B Polyclonal Antibody (PACO11408) is a valuable tool for researchers studying PPM1B, a key phosphatase enzyme involved in regulating cellular processes such as cell cycle progression, apoptosis, and stress responses. This antibody, produced in rabbits, exhibits high specificity and affinity for human samples, making it suitable for Western blot applications.PPM1B, also known as protein phosphatase magnesium-dependent 1B, plays a crucial role in modulating signaling pathways involved in cell growth, differentiation, and survival. Dysregulation of PPM1B has been linked to various diseases, including cancer and neurodegenerative disorders, making it an intriguing target for further investigation.
By targeting the PPM1B protein, researchers can gain insights into its functions and mechanisms of action, paving the way for potential therapeutic interventions aimed at restoring normal cellular processes in disease conditions. The PPM1B Polyclonal Antibody (PACO11408) offers a reliable tool for studying PPM1B expression levels and localization in various cell types, contributing to advancements in biomedical research.
protein phosphatase 1B (formerly 2C), magnesium-dependent, β isoform;PPM1B;MGC21657;PP2C-beta-X;PP2CB;PP2CBETA;PPC2BETAX ;
UniProt Protein Function:
Function: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit By similarity. HAMAP-Rule MF_01326One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit By similarity. HAMAP-Rule MF_01326Subunit structure: Part of the 50S ribosomal subunit By similarity. HAMAP-Rule MF_01326Sequence similarities: Belongs to the ribosomal protein L24P family.