The PPP1R18 Monoclonal Antibody (MACO0333) is a valuable tool for researchers studying PPP1R18, a protein involved in cell cycle regulation and cellular signaling. This monoclonal antibody, produced in mice, exhibits high specificity and sensitivity for detecting PPP1R18 in human samples, making it an excellent choice for experiments such as Western blotting and immunofluorescence.PPP1R18, also known as regulatory subunit 18 of protein phosphatase 1, plays a key role in controlling cell division and DNA replication. Its dysregulation has been linked to various diseases, including cancer and neurodegenerative disorders.
By using the PPP1R18 Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of PPP1R18, advancing our understanding of its role in health and disease.This antibody offers researchers a reliable and accurate tool for studying PPP1R18 in a variety of experimental settings, from basic research to drug development. Its high specificity and sensitivity make it a valuable asset for investigating the molecular mechanisms underlying PPP1R18 function, paving the way for potential therapeutic interventions targeting this important protein.
Product Name:
Anti-PPP1R18 Antibody
Product Sku:
MACO0333
Size:
100ul
Host Species:
Mouse
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:5000
Species Reactivity:
Human
Immunogen:
Purified recombinant human PPP1R18 protein fragments expressed in E.coli.
Form:
Liquid
Storage Buffer:
Ascites
Purification Method:
Affinity purified
Clonality:
Monoclonal
Isotype:
IgG1
Conjugate:
Non-conjugated
Background:
May target protein phosphatase 1 to F-actin cytoskeleton.
Synonyms:
HKMT1098; KIAA1949; Protein phosphatase 1 F actin cytoskeleton targeting subunit; PPP1R18;
UniProt Protein Function:
PPP1R18: May target protein phosphatase 1 to F-actin cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 6p21.3 Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]
