The PRAP1 Polyclonal Antibody (CAB8770) is specifically designed for research involving PRAP1, a protein involved in DNA repair and apoptosis regulation. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot and immunofluorescence.PRAP1, also known as proline-rich acidic protein 1, plays a critical role in maintaining genomic stability and cell survival through its involvement in DNA damage response pathways. Dysregulation of PRAP1 has been linked to various diseases including cancer, making it an important target for research in oncology and molecular biology.
By using the PRAP1 Polyclonal Antibody, researchers can effectively detect and analyze PRAP1 protein levels in different cell types, providing valuable insights into its function and potential therapeutic implications. This antibody is a valuable tool for studying PRAP1's role in DNA repair mechanisms and its impact on cell proliferation and survival, offering new possibilities for developing targeted therapies for cancer and other diseases.
Product Name:
PRAP1 Rabbit Polyclonal Antibody
SKU:
CAB8770
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human PRAP1 (NP_660203.3).
Predicted to enable triglyceride binding activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; deactivation of mitotic spindle assembly checkpoint; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum and extracellular region.
Purification Method:
Affinity purification
Gene ID:
118471
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRAP1 Rabbit pAb (CAB8770) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
