Based on the information provided in the URL, here is a product description:The PRELID3B Polyclonal Antibody (PAC042670) is a cutting-edge research tool designed for scientists studying PRELID3B, a protein involved in mitochondrial protein import and processing. This antibody, generated through rabbit immunization, exhibits high specificity and sensitivity when detecting PRELID3B in human samples, making it an excellent choice for Western blot experiments. By targeting the PRELID3B protein, researchers can efficiently monitor and analyze its expression levels in various cell types, facilitating investigations in mitochondrial biology and related research areas.PRELID3B, also known as the mitochondrial import inner membrane translocase subunit TIM16, plays a vital role in maintaining mitochondrial function and protein transport within the cell.
Its involvement in these essential processes underscores its relevance in studies focused on mitochondrial disorders, metabolic diseases, and cellular metabolism. By elucidating the function and regulation of PRELID3B, researchers can gain valuable insights into the mechanisms underlying mitochondrial dysfunction and identify potential therapeutic targets for various diseases associated with mitochondrial impairment.Overall, the PRELID3B Polyclonal Antibody (PAC042670) offers a reliable and efficient tool for scientists seeking to deepen their understanding of mitochondrial biology and explore novel avenues in mitochondrial research. Its versatility and robust performance make it a valuable asset for scientific investigations aiming to unravel the complexities of mitochondrial protein import and processing.
Antibody Name:
PRELID3B Antibody (PACO42670)
Antibody SKU:
PACO42670
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human PRELI domain containing protein 3B protein (1-194AA)
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria. [provided by RefSeq, Jul 2008]
