The Prickle2 Polyclonal Antibody (CAB8023) is a valuable tool for researchers studying Prickle2, a protein known for its involvement in various cellular processes including cell polarity and development. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications. It specifically binds to the Prickle2 protein, allowing for accurate detection and analysis in a variety of cell types.Prickle2, a key player in the Wnt signaling pathway, is essential for proper development and morphogenesis. Dysregulation of Prickle2 has been linked to various diseases, making it an important target for research in developmental biology and cancer.
By understanding the function and regulation of Prickle2, researchers can gain insights into the underlying mechanisms of diseases and potentially identify new therapeutic targets.Overall, the Prickle2 Polyclonal Antibody (CAB8023) is a reliable tool for investigating the role of Prickle2 in cellular processes and diseases. Its high specificity and reactivity make it an ideal choice for studies in molecular biology, developmental biology, and cancer research.
Product Name:
PRICKLE2 Rabbit Polyclonal Antibody
SKU:
CAB8023
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 615-844 of human PRICKLE2 (NP_942559.1).
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5.
Purification Method:
Affinity purification
Gene ID:
166336
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PRICKLE2 antibody (CAB8023) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
