Description
system_update_altDatasheet
| Product name | Human PROKR1 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP083 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | PROKR1 |
| Uniprot: | Q8TCW9 |
| Description: | Human PROKR1 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length PROKR1 protein has a MW of 44.6 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | GPR73; GPR73a; PK-R1; PKR1; ZAQ |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | This gene encodes a member of the G-protein-coupled receptor family. The encoded protein binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. The encoded protein is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. The protein may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in this gene may be associated with recurrent miscarriage. [provided by RefSeq, Aug 2016] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
