The PROCR Antibody (CAB5763) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the ProCR protein, this antibody enables researchers to detect and analyze ProCR expression in various cell types, making it a valuable tool for studies in immunology and cancer research.ProCR, also known as a key regulator of inflammation, plays a crucial role in modulating immune responses and maintaining immune homeostasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
PROCR Antibody
SKU:
CAB5763
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CCCA, EPCR, CCD41, PROCR
Positive Sample:
MCF7, HepG2, HeLa, 293T, Mouse kidney
Cellular Localization:
Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
27kDa
Observed MW:
45kDa
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
Purification Method
Affinity purification
Gene ID
10544
RRID
AB_2766517
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PROCR Rabbit pAb (CAB5763) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
