The PRPS2 Antibody (CAB12644) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human PRPS2 and has been validated for use in Western blotting applications.PRPS2 plays a crucial role in maintaining nucleotide pools for DNA and RNA synthesis, making it essential for cell proliferation and growth. Dysregulation of PRPS2 has been implicated in various diseases, including cancer and metabolic disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PRPS2 Antibody
SKU:
CAB12644
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PRSII, PRPS2
Positive Sample:
HeLa, MCF7, Mouse brain, Mouse heart, Mouse kidney, Rat liver
Cellular Localization:
Cytoplasm, Cytosol.
Calculated MW:
35kDa
Observed MW:
35kDa
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
5634
RRID
AB_2759489
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRPS2 Rabbit pAb (CAB12644) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
