Description
PRTFDC1 Antibody (PACO11511)
The PRTFDC1 Antibody (PAC011511) is a valuable tool for researchers studying the PRTFDC1 protein, which plays a crucial role in various cellular processes. This polyclonal antibody is raised in rabbits and has been extensively validated for use in Western blot applications. It specifically binds to the PRTFDC1 protein, enabling accurate detection and analysis in a wide range of cell types.PRTFDC1 is involved in DNA damage response and repair mechanisms, making it a key player in maintaining genomic stability. Dysregulation of PRTFDC1 has been linked to various diseases, including cancer and neurodegenerative disorders.
Therefore, studying the function of PRTFDC1 is essential for gaining insights into disease mechanisms and developing targeted therapies.Researchers in the fields of genetics, molecular biology, and oncology will benefit from using the PAC011511 antibody to investigate the role of PRTFDC1 in normal cellular processes and disease pathogenesis. With its high specificity and sensitivity, this antibody is a valuable tool for advancing scientific knowledge and discovering new therapeutic targets.
| Antibody Name: | PRTFDC1 Antibody (PACO11511) |
| Antibody SKU: | PACO11511 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human PRTFDC1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | phosphoribosyl transferase domain containing 1;PRTFDC1;FLJ11888;HHGP ; |
| UniProt Protein Function: | PRTFDC1: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. Belongs to the purine/pyrimidine phosphoribosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 10p12.1 Cellular Component: cytosol Molecular Function:hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity Biological Process: adenine salvage; GMP catabolic process; GMP salvage; guanine salvage; hypoxanthine metabolic process; IMP salvage |
| UniProt Code: | Q9NRG1 |
| NCBI GenInfo Identifier: | 74752920 |
| NCBI Gene ID: | 56952 |
| NCBI Accession: | Q9NRG1.1 |
| UniProt Secondary Accession: | Q9NRG1,Q53HA7, Q59EL9, Q5VV18, Q5VV20, B7Z1Z3, |
| UniProt Related Accession: | Q9NRG1 |
| Molecular Weight: | 19,983 Da |
| NCBI Full Name: | Phosphoribosyltransferase domain-containing protein 1 |
| NCBI Synonym Full Names: | phosphoribosyl transferase domain containing 1 |
| NCBI Official Symbol: | PRTFDC1Â Â |
| NCBI Official Synonym Symbols: | HHGPÂ Â |
| NCBI Protein Information: | phosphoribosyltransferase domain-containing protein 1 |
| UniProt Protein Name: | Phosphoribosyltransferase domain-containing protein 1 |
| Protein Family: | Phosphoribosyltransferase domain-containing protein |
| UniProt Gene Name: | PRTFDC1Â Â |
| UniProt Entry Name: | PRDC1_HUMAN |
