The PSPH Antibody (CAB7924) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.PSPH plays a crucial role in cellular metabolism, specifically in the regulation of serine levels which are essential for cell proliferation and survival. Dysregulation of PSPH has been implicated in various diseases, including cancer and metabolic disorders. By targeting the PSPH protein, researchers can gain insights into the role of serine metabolism in disease progression and potentially identify new therapeutic targets.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
PSPH Antibody
SKU:
CAB7924
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
PSP, PSPHD, PSPH
Positive Sample:
HepG2, A-431, HeLa, Mouse thymus, Mouse spleen, Rat kidney
Cellular Localization:
Cytoplasm, Cytosol, Neuron Projection.
Calculated MW:
25kDa
Observed MW:
26kDa
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.
Purification Method
Affinity purification
Gene ID
5723
RRID
AB_2771862
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using PSPH Rabbit pAb (CAB7924) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
