Description
PSPN Antibody (PACO13578)
The PSPN Antibody (PAC013578) is a polyclonal antibody designed for research involving PSPN, a protein associated with nervous system development and function. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in various applications including Western blotting.PSPN, also known as persephin, is a neurotrophic factor that plays a crucial role in promoting the survival and differentiation of neurons, particularly in the peripheral nervous system. Studies have shown that PSPN is involved in neuronal development, regeneration, and repair, making it a promising target for research in neuroscience and neurodegenerative diseases.
By using the PSPN Antibody, researchers can detect and analyze PSPN protein expression in different cell types and tissues, providing valuable insights into its function and potential therapeutic applications. This antibody is a valuable tool for studies related to nervous system disorders, neural development, and neuroprotection.
| Antibody Name: | PSPN Antibody (PACO13578) |
| Antibody SKU: | PACO13578 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Human PSPN-Specific |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | persephin;PSPN;PSP ; |
| UniProt Protein Function: | PSPN: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons. Belongs to the TGF-beta family. GDNF subfamily. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: extracellular space Molecular Function:growth factor activity; receptor binding Biological Process: nervous system development; axon guidance; central nervous system development; ureteric bud branching |
| NCBI Summary: | The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60542 |
| NCBI GenInfo Identifier: | 7531178 |
| NCBI Gene ID: | 5623 |
| NCBI Accession: | O60542.1 |
| UniProt Related Accession: | O60542 |
| Molecular Weight: | 16,600 Da |
| NCBI Full Name: | Persephin |
| NCBI Synonym Full Names: | persephin |
| NCBI Official Symbol: | PSPNÂ Â |
| NCBI Official Synonym Symbols: | PSPÂ Â |
| NCBI Protein Information: | persephin |
| UniProt Protein Name: | Persephin |
| Protein Family: | Persephin |
| UniProt Gene Name: | PSPNÂ Â |
| UniProt Entry Name: | PSPN_HUMAN |
