The Parathyroid Hormone (PTH) Antibody (CAB5846) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human parathyroid hormone and has been validated for use in various applications such as Western blotting.Parathyroid hormone plays a crucial role in maintaining calcium levels in the blood and bone, making it a critical hormone for overall bone health and mineral balance. Dysregulation of parathyroid hormone can lead to disorders such as hyperparathyroidism or hypoparathyroidism, which can have serious implications for bone health and overall well-being.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
Parathyroid Hormone (PTH) Antibody
SKU:
CAB5846
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
FIH1, PTH1, Parathyroid Hormone (PTH)
Positive Sample:
U-251MG, 293T
Cellular Localization:
Secreted.
Calculated MW:
13kDa
Observed MW:
14kDa
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
5741
RRID
AB_2766596
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Parathyroid Hormone (PTH) Rabbit pAb (CAB5846) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
