The PTX3 Polyclonal Antibody (CAB12670) is a valuable tool for researchers studying PTX3, a protein involved in the immune response and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the PTX3 protein, this antibody allows for the precise detection and analysis of PTX3 in various cell types, making it an excellent choice for studies in immunology and inflammatory disease research.
PTX3, also known as pentraxin-related protein 3, is a key player in the regulation of immune responses and inflammatory processes. Its involvement in these pathways makes it a promising target for investigation in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying the role of PTX3, researchers can gain insights into potential therapeutic interventions that modulate the immune system and combat these conditions effectively.
Product Name:
PTX3 Rabbit Polyclonal Antibody
SKU:
CAB12670
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-240 of human PTX3 (NP_002843.2).
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
Purification Method:
Affinity purification
Gene ID:
5806
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse liver, using PTX3 Rabbit pAb (CAB12670) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
