Description
| Product Title: | Purified Anti-Human CD34 Antibody [4H11] | 
| SKU: | AGEL3517 | 
| Size: | 25µg, 100µg | 
| Clone No: | 4H11 | 
| Synonyms: | Gp105-120; My10; | 
| Host Species: | Mouse | 
| Reactivity: | Human | 
| Application: | FCM | 
| Isotype: | Mouse IgG1, κ | 
| Isotype Control: | Purified Mouse IgG1, κ Isotype Control[MOPC-21] | 
| Form: | Liquid | 
| Conjugation: | Unconjugated | 
| Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. | 
| Swissprot: | P28906 | 
| Gene ID: | 947 | 
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. | 
| Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. | 
| Background: | CD34, also known as gp105-120, is a type I monomeric sialomucin-like glycophosphoprotein with an approximate molecular weight of 105-120 kD. Selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nervous tissue, CD34 is a commonly used marker to identify human hematopoietic stem/progenitor cells. According to the differential sensitivity to enzymatic cleavage, four groups of epitopes of CD34 have been described. CD34 mediates cell adhesion and lymphocytes homing through binding to L-selectin and E-selectin ligands. |