The PXMP2 Polyclonal Antibody (PAC02294) offered by AssayGenie is a valuable tool for researchers studying PXMP2, a peroxisomal membrane protein involved in various cellular processes. This antibody is raised in rabbits and demonstrates high reactivity with human samples, making it an ideal choice for Western blot applications. By binding specifically to the PXMP2 protein, this antibody enables precise detection and analysis in a variety of cell types, facilitating research in the fields of cell biology and metabolism.PXMP2 plays a crucial role in peroxisomal function, contributing to processes such as lipid metabolism and cellular detoxification. Dysfunction or dysregulation of PXMP2 has been implicated in disorders related to peroxisomal biogenesis and metabolism, making it a promising target for therapeutic interventions.
By elucidating the mechanisms underlying PXMP2 activity, researchers can gain insights into the pathophysiology of peroxisomal disorders and potentially develop novel treatment strategies.Overall, the PXMP2 Polyclonal Antibody (PAC02294) from AssayGenie is a reliable reagent for investigating the function and regulation of PXMP2 in various cellular contexts. Its specificity and high sensitivity make it a valuable asset for researchers interested in exploring the role of peroxisomes in health and disease.
Antibody Name:
PXMP2 Antibody (PACO22494)
Antibody SKU:
PACO22494
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human PXMP2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PXMP2 antibody.
Background:
Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane.
Synonyms:
Peroxisomal membrane protein 2; 22 kDa peroxisomal membrane protein;
UniProt Protein Function:
PXMP2: Seems to be involved in pore-forming activity and may contribute to the unspecific permeability of the peroxisomal membrane. Belongs to the peroxisomal membrane protein PXMP2/4 family.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12q24.33Cellular Component: cytoplasm; membrane; peroxisomal membrane; protein complexMolecular Function: protein binding
