The Rab11Fip2 Polyclonal Antibody (PACO11631) is a valuable tool for researchers studying Rab11Fip2, a protein involved in intracellular trafficking and membrane recycling processes. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.Rab11Fip2 is a member of the Rab11 family of small GTPases, which play a crucial role in regulating vesicular trafficking and membrane dynamics. Rab11Fip2 is specifically involved in the recycling of endosomes and is important for maintaining cellular homeostasis.
Dysregulation of Rab11Fip2 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a prime target for further investigation.By using the Rab11Fip2 Polyclonal Antibody, researchers can easily detect and analyze Rab11Fip2 expression in different cell types and tissues, providing valuable insights into its function and potential roles in disease pathology. This antibody is a valuable tool for those studying intracellular trafficking, membrane dynamics, and diseases associated with Rab11Fip2 dysfunction.
RAB11 family interacting protein 2 (class I);RAB11FIP2;KIAA0941;Rab11-FIP2;nRip11 ;
UniProt Protein Function:
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
