The Rab29 Polyclonal Antibody (PAC022558) is a valuable tool for researchers studying the Rab29 protein, a key regulator of intracellular membrane trafficking pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in immunofluorescence and immunohistochemistry applications.Rab29 is known to be involved in the transport of vesicles between cellular compartments, playing a critical role in maintaining cellular homeostasis and organelle function. Dysregulation of Rab29 has been linked to various diseases, including neurodegenerative disorders and infectious diseases, making it a promising target for therapeutic interventions.
By targeting the Rab29 protein, researchers can gain valuable insights into the mechanisms underlying cellular trafficking processes and potentially identify novel therapeutic strategies for treating diseases associated with Rab29 dysfunction. The Rab29 Polyclonal Antibody offers researchers a reliable tool for investigating the function and regulation of Rab29 in various cell types and tissues, making it an essential component of studies in cell biology and disease pathology.
Antibody Name:
RAB29 Antibody (PACO22558)
Antibody SKU:
PACO22558
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human RAB7L1.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HT-29 cells, using RAB7L1 antibody.
Synonyms:
RAB7; member RAS oncogene family-like 1; RAB7L;
UniProt Protein Function:
RAB7L1: Belongs to the small GTPase superfamily. Rab family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: G protein, monomeric; G protein, monomeric, Rab; G proteinChromosomal Location of Human Ortholog: 1q32Cellular Component: cytoskeleton; mitochondrion; perinuclear region of cytoplasm; cytoplasm; melanosome; plasma membrane; vacuole; trans-Golgi networkMolecular Function: GTPase activity; protein binding; GDP binding; GTP bindingBiological Process: protein transport; ER to Golgi vesicle-mediated transport; melanosome organization and biogenesis; metabolic process; cell differentiation; Rab protein signal transduction; Golgi organization and biogenesis
