Description
RAB3C Antibody (PACO11657)
The Rab3C Polyclonal Antibody (PACO11657) is a valuable tool for researchers studying Rab3C, a small GTPase protein involved in the regulation of intracellular membrane traffic. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting Rab3C in human samples, making it ideal for use in Western blot and immunohistochemistry applications.Rab3C plays a key role in vesicle trafficking and neurotransmitter release in neuronal cells, making it a crucial player in synaptic transmission and plasticity. Dysregulation of Rab3C has been linked to neurological disorders such as Alzheimer's disease and Parkinson's disease, highlighting its importance in understanding the pathophysiology of these conditions.
By utilizing the Rab3C Polyclonal Antibody, researchers can investigate the function and localization of Rab3C in various cell types and tissues, furthering our knowledge of its roles in cellular processes. This antibody is a valuable tool for studies in neuroscience, cell biology, and neurodegenerative diseases, providing insights that may lead to the development of new therapeutic strategies for neurological disorders.
| Antibody Name: | RAB3C Antibody (PACO11657) |
| Antibody SKU: | PACO11657 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human RAB3C |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | RAB3C, member RAS oncogene family; |
| UniProt Protein Function: | RAB3C: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family. |
| UniProt Protein Details: | Protein type:G protein; G protein, monomeric, Rab; G protein, monomeric Chromosomal Location of Human Ortholog: 5q13 Cellular Component: synaptic vesicle; secretory granule membrane; perinuclear region of cytoplasm; plasma membrane; cytosol; vesicle; endosome Molecular Function:GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding Biological Process: regulation of exocytosis; intracellular protein transport; antigen processing and presentation; synaptic vesicle exocytosis; metabolic process; protein secretion; Rab protein signal transduction; vesicle docking during exocytosis |
| NCBI Summary: | This gene is a member of the RAS oncogene family and encodes a small GTPase. Other similar small GTPases are known to be involved in vesicle trafficking, and the encoded protein was shown to play a role in recycling phagocytosed MHC class 1 complexes to the cell surface. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| UniProt Code: | Q96E17 |
| NCBI GenInfo Identifier: | 23396832 |
| NCBI Gene ID: | 115827 |
| NCBI Accession: | Q96E17.1 |
| UniProt Related Accession: | Q96E17 |
| Molecular Weight: | |
| NCBI Full Name: | Ras-related protein Rab-3C |
| NCBI Synonym Full Names: | RAB3C, member RAS oncogene family |
| NCBI Official Symbol: | RAB3CÂ Â |
| NCBI Protein Information: | ras-related protein Rab-3C |
| UniProt Protein Name: | Ras-related protein Rab-3C |
| Protein Family: | Ras-related protein |
| UniProt Gene Name: | RAB3CÂ Â |
| UniProt Entry Name: | RAB3C_HUMAN |
