The Rab6B Polyclonal Antibody (PAC041170) is a valuable tool for researchers studying Rab6B, a small GTPase protein involved in intracellular vesicle trafficking and membrane dynamics. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to Rab6B, this antibody enables the detection and analysis of this protein in various cell types, making it an essential tool for studies in cell biology and membrane trafficking research.Rab6B plays a crucial role in regulating transport vesicle docking and fusion at the Golgi apparatus, as well as in endosome-to-TGN trafficking pathways. Its involvement in these processes makes Rab6B a key player in maintaining cellular homeostasis and organelle function.
Research into the functions and regulation of Rab6B is essential for understanding the mechanisms underlying intracellular trafficking and organelle dynamics, with implications in various cellular processes and diseases.Overall, the Rab6B Polyclonal Antibody (PAC041170) is a reliable reagent for investigating the functions and roles of Rab6B in cellular processes, offering valuable insights into membrane trafficking and organelle dynamics. Its specificity and sensitivity make it an ideal tool for researchers aiming to unravel the complexities of intracellular vesicle transport and organelle function.
Western blot. All lanes: RAB6B antibody at 5µg/ml. Lane 1: Mouse brain tissue. Lane 2: U251 whole cell lysate. Lane 3: MCF-7 whole cell lysate. Lane 4: A549 whole cell lysate. Lane 5: K562 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 24, 23 kDa. Observed band size: 24 kDa.
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO41170 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO41170 at dilution of 1:100.
Background:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.
Synonyms:
Ras-related protein Rab-6B, RAB6B
UniProt Protein Function:
RAB6B: Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells. Belongs to the small GTPase superfamily. Rab family.Protein type: G protein, monomeric, Rab; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: 3q22.1Cellular Component: Golgi apparatusMolecular Function: myosin V binding; protein bindingBiological Process: intra-Golgi vesicle-mediated transport; retrograde transport, endosome to Golgi; retrograde vesicle-mediated transport, Golgi to ER
