The Rab9B Polyclonal Antibody (PACO11674) is a valuable tool for research focused on Rab9B, a small GTPase protein involved in intracellular vesicle trafficking. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for various research applications.Rab9B is known to play a critical role in the late endocytic pathway, specifically in the transport of mannose-phosphate receptor from endosomes to the trans-Golgi network. Dysregulation of Rab9B has been linked to various diseases, including neurodegenerative disorders and cancer.
By using the Rab9B Polyclonal Antibody, researchers can investigate the localization and function of Rab9B in different cell types, aiding in the understanding of its role in disease pathology.Overall, the Rab9B Polyclonal Antibody is a valuable tool for studying intracellular trafficking pathways and their implications in disease development. Its specificity and reliability make it an essential component for research in cell biology, molecular biology, and drug discovery.
Function: Involved in the transport of proteins between the endosomes and the trans Golgi network By similarity.Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side Potential. Cytoplasmic vesicle › phagosome. Cytoplasmic vesicle › phagosome membrane; Lipid-anchor; Cytoplasmic side By similarity. Note: Recruited to phagosomes containing S.aureus or M.tuberculosis. Ref.5Tissue specificity: Ubiquitous. Ref.1Sequence similarities: Belongs to the small GTPase superfamily. Rab family.
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of a subfamily of RAS small guanosine triphosphate (GTP)-binding proteins that regulate membrane trafficking. The encoded protein may be involved in endosome-to-Golgi transport. [provided by RefSeq, Jan 2010]
