Description
RABEP1 Antibody (PACO11676)
The RABEP1 Polyclonal Antibody (PACO11676) is a valuable tool for researchers studying the RABEP1 protein, which plays a key role in regulating membrane traffic and endocytosis. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in Western blot applications. By binding to the RABEP1 protein, this antibody allows for the detection and analysis of RABEP1 in various cell types, making it ideal for studies in cell biology and molecular biology.
RABEP1 is a crucial component involved in the intracellular trafficking of vesicles, particularly in the endocytic pathway. Its role in regulating membrane dynamics and protein sorting makes it a target of interest in research related to cell trafficking, signaling, and disease mechanisms. By studying RABEP1, researchers can gain insights into cellular processes and potentially identify new therapeutic targets for diseases related to membrane trafficking dysfunction.
| Antibody Name: | RABEP1 Antibody (PACO11676) |
| Antibody SKU: | PACO11676 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human RABEP1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | rabaptin, RAB GTPase binding effector protein 1;RABEP1;RAB5EP;RABPT5 ; |
| UniProt Protein Function: | RABEP1: Rab effector protein acting as linker between gamma- adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 17p13.2 Cellular Component: recycling endosome; intracellular membrane-bound organelle; endocytic vesicle; early endosome; endosome Molecular Function:protein binding; protein homodimerization activity; growth factor activity; GTPase activator activity Biological Process: vesicle-mediated transport; protein transport; apoptosis; endocytosis; positive regulation of GTPase activity |
| UniProt Code: | Q15276 |
| NCBI GenInfo Identifier: | 116242743 |
| NCBI Gene ID: | 9135 |
| NCBI Accession: | Q15276.2 |
| UniProt Secondary Accession: | Q15276,O95369, Q8IVX3, B2RAG7, |
| UniProt Related Accession: | Q15276 |
| Molecular Weight: | 862 |
| NCBI Full Name: | Rab GTPase-binding effector protein 1 |
| NCBI Synonym Full Names: | rabaptin, RAB GTPase binding effector protein 1 |
| NCBI Official Symbol: | RABEP1Â Â |
| NCBI Official Synonym Symbols: | RAB5EP; RABPT5Â Â |
| NCBI Protein Information: | rab GTPase-binding effector protein 1; rabaptin-4; rabaptin-5; neurocrescin; rabaptin-5alpha; renal carcinoma antigen NY-REN-17 |
| UniProt Protein Name: | Rab GTPase-binding effector protein 1 |
| UniProt Synonym Protein Names: | Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17 |
| Protein Family: | Rab GTPase-binding effector protein |
| UniProt Gene Name: | RABEP1Â Â |
| UniProt Entry Name: | RABE1_HUMAN |
