The RABEP2 Polyclonal Antibody (PAC022536) is a valuable tool for researchers studying RABEP2, a protein involved in intracellular membrane trafficking and regulation. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for Western blot applications. By targeting the RABEP2 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an ideal choice for investigations in cell biology and molecular biology.
RABEP2 plays a crucial role in vesicle transport and membrane fusion processes within cells, making it a key player in maintaining cellular homeostasis and functioning. Its involvement in intracellular trafficking pathways suggests its potential relevance in diseases such as neurodegenerative disorders and metabolic diseases. By studying RABEP2 using this antibody, researchers can uncover more about its function and potential implications in various cellular processes and disease states.
Antibody Name:
RABEP2 Antibody (PACO22536)
Antibody SKU:
PACO22536
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from internal of human RABEP2.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HeLa cells, Jurkat cells, 293 cells and HUVEC cells, using RABEP2 antibody.
Background:
Plays a role in membrane trafficking and in homotypic early endosome fusion.
Synonyms:
rab GTPase-binding effector protein 2; rabaptin-5beta; rabe2; rabpt5b;
UniProt Protein Function:
RABEP2: Plays a role in membrane trafficking and in homotypic early endosome fusion. Belongs to the rabaptin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rab; GAPsChromosomal Location of Human Ortholog: 16p11.2Cellular Component: intracellular membrane-bound organelle; early endosome; cytoplasmMolecular Function: growth factor activity; GTPase activator activityBiological Process: protein transport; endocytosis; positive regulation of GTPase activity
