The Rad51AP1 Polyclonal Antibody (PAC011695) is a valuable tool for researchers studying the protein Rad51AP1, which plays a key role in DNA repair and homologous recombination. This antibody, produced in rabbits, specifically targets Rad51AP1 and is highly reactive with human samples. Validated for use in Western blot applications, the antibody allows for the detection and analysis of Rad51AP1 in various cell types.Rad51AP1 is essential for the proper functioning of the homologous recombination pathway, which is crucial for maintaining genome integrity and preventing the accumulation of DNA damage. Dysregulation of Rad51AP1 has been implicated in various diseases, including cancer, where defects in DNA repair mechanisms can lead to genomic instability and tumor development.
By studying the role of Rad51AP1, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new targets for therapeutic intervention.With its high specificity and sensitivity, the Rad51AP1 Polyclonal Antibody is an invaluable tool for investigating the function of Rad51AP1 in cellular processes related to DNA repair and genome maintenance. Its versatility and reliability make it an ideal choice for researchers in the fields of molecular biology, genetics, and oncology who are interested in unraveling the intricate mechanisms of DNA repair pathways.
RAD51AP1: May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Functionally cooperates with PALB2 in promoting of D-loop formation by RAD51. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 12p13.2-p13.1Cellular Component: nucleusMolecular Function: protein binding; RNA binding; double-stranded DNA binding; single-stranded DNA bindingBiological Process: DNA repair; double-strand break repair via homologous recombination
