The RAP2C Polyclonal Antibody (PACO01409) is a valuable tool for researchers studying RAP2C, a protein involved in cell signaling pathways and regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the RAP2C protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in cell biology, signal transduction, and cancer research.RAP2C is a small GTPase that plays a role in cellular processes such as cell migration, proliferation, and cytoskeletal dynamics.
Its involvement in these pathways makes it a compelling target for investigation in various diseases, including cancer. Understanding the function and regulation of RAP2C is essential for uncovering its potential role in disease progression and developing targeted therapies. The RAP2C Polyclonal Antibody provides a reliable tool for researchers to explore the intricate mechanisms involving RAP2C and its implications in cellular biology and disease.
Antibody Name:
RAP2C Antibody
Antibody SKU:
PACO01409
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human Rap 2C.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
RAP2C; Ras-related protein Rap-2c
UniProt Protein Function:
RAP2C: Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. May play a role in cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK. May play a role in SRE-mediated gene transcription. Belongs to the small GTPase superfamily. Ras family.Protein type: G protein, monomeric, Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: Xq25Cellular Component: cytoplasm; cytosol; plasma membrane; recycling endosome membrane; tight junctionMolecular Function: GDP binding; GTP binding; transcription coactivator activityBiological Process: microvillus biogenesis; negative regulation of cell migration; positive regulation of protein amino acid autophosphorylation; Rap protein signal transduction
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]
