The RAPGEF6 Antibody (CAB17161) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the Rapgef6 protein, this antibody enables the detection and analysis of Rapgef6 expression in various cell types, making it ideal for investigations into cell signaling, cancer biology, and developmental biology.Rapgef6, also known as Epac2, is a guanine nucleotide exchange factor that plays a crucial role in the regulation of cAMP signaling pathways, which are implicated in diverse cellular processes such as cell proliferation, differentiation, and survival.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
RAPGEF6 Antibody
SKU:
CAB17161
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Enables several functions, including GTP-dependent protein binding activity; guanyl-nucleotide exchange factor activity; and phosphatidic acid binding activity. Involved in microvillus assembly; positive regulation of GTPase activity; and protein localization to plasma membrane. Located in several cellular components, including apical plasma membrane; centrosome; and endocytic vesicle.
Purification Method
Affinity purification
Gene ID
51735
RRID
AB_2771939
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using RAPGEF6 Rabbit pAb (CAB17161) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
