The RASSF9 Polyclonal Antibody (PAC016948) is a valuable tool for researchers studying RASSF9, a member of the RASSF family of proteins that are known for their tumor-suppressor properties. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.RASSF9 is a key player in cell cycle regulation, apoptosis, and the suppression of tumor growth, making it a promising target for cancer research. By specifically binding to the RASSF9 protein, this antibody enables researchers to detect and analyze its expression in various cell types, providing insights into its role in tumorigenesis and potential as a therapeutic target.
With its ability to facilitate the study of RASSF9 in cancer biology and related fields, the PAC016948 antibody is a valuable resource for advancing our understanding of tumor development and potentially identifying new strategies for cancer treatment.
Antibody Name:
RASSF9 Antibody (PACO16948)
Antibody SKU:
PACO16948
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Fusion protein of human RASSF9
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16948(RASSF9 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16948(RASSF9 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways.
Synonyms:
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
UniProt Protein Function:
RASSF9: May play a role in regulating vesicuar trafficking in cells.Chromosomal Location of Human Ortholog: 12q21.31Cellular Component: trans-Golgi network transport vesicle membrane; cytosol; endosomeMolecular Function: protein binding; transporter activityBiological Process: signal transduction; endosome transport; protein targeting
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene localizes to perinuclear endosomes. This protein associates with peptidylglycine alpha-amidating monooxygenase, and may be involved with the trafficking of this enzyme through secretory or endosomal pathways. [provided by RefSeq, Jul 2008]
