The RBM14 Antibody (CAB4418) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting RBM14 in human samples, making it a valuable asset for experiments involving Western blot analyses.RBM14 is known to interact with various RNA molecules, influencing processes like splicing and mRNA stability. Its dysregulation has been implicated in diseases such as cancer, making it a prime target for further investigation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
RBM14 Antibody
SKU:
CAB4418
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SIP, COAA, PSP2, SYTIP1, TMEM137, RBM14
Positive Sample:
HeLa, 293T, Jurkat, Mouse thymus, Rat testis
Cellular Localization:
Nucleus, Nucleolus.
Calculated MW:
69kDa
Observed MW:
75kDa
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Purification Method
Affinity purification
Gene ID
10432
RRID
AB_2765664
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using RBM14 Rabbit pAb (CAB4418) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
