The RECK Antibody (CAB6718) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the RECK protein, this antibody allows for accurate detection and analysis in various cell types, making it an essential tool for studies in cancer research and beyond.RECK, also known as reversion-inducing cysteine-rich protein with kazal motifs, is a critical regulator of extracellular matrix turnover and cell migration, playing a central role in tumor invasion and metastasis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
RECK Antibody
SKU:
CAB6718
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
ST15, RECK
Positive Sample:
293T, MCF-7, H460, Mouse lung, Mouse kidney
Cellular Localization:
Cell Membrane, Gpi-Anchor, Lipid-Anchor.
Calculated MW:
106kDa
Observed MW:
106kDa
The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
8434
RRID
AB_2767302
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.