Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
Product Name:
Human C1QBP Recombinant Protein (RPES2490)
Product Code:
RPES2490
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial, ASF/SF2-Associated Protein p32, Glycoprotein gC1qBP, C1qBP, Hyaluronan-Binding Protein 1, Mitochondrial Matrix Protein p32, gC1q-R Protein, p33, C1QBP, GC1QBP, HABP1, SF2P32,gC1qR
Accession:
NP_001203.1
Sequence:
Leu74-Gln282
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Hyaluronic Acid-binding Protein is produced by our E.coli expression system and the target gene encoding Leu74-Gln282 is expressed with a 6His tag at the C-terminus.
Purity:
> 85 % as determined by reducing SDS-PAGE.
Mol Mass:
24.9 kDa
AP Mol Mass:
34 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris, 20% Glycerol, 1mM DTT, pH 7.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
