Description
| Product Name: | Recombinant Human CCL27 Protein (Trx Tag) |
| SKU: | RPES8036 |
| Size: | 20μg |
| Tag: | N-Trx |
| Reactivity: | Human |
| Expression Host: | E.coli |
| Accession: | Q9Y4X3 |
| Sequence: | Phe25-Gly112 |
| Calculated Molecular Weight: | 29.6 kDa |
| Observed Molecular Weight: | 31 kDa |
| Synonyms: | ALP, C-C motif chemokine 27, CC chemokine ILC, Ccl27, CCL27, Chemokine (C-C motif) ligand 27, CTACK, CTAK, Cutaneous T cell attracting chemokine, Cutaneous T-cell-attracting chemokine, ESkine, IL 11 R alpha locus chemokine, IL-11 R-alpha-locus chemokine, ILC, PESKY, SCYA27, Skinkine, Small inducible cytokine A27, small inducible cytokine subfamily A (Cys-Cys), member 27, Small-inducible cytokine A27 |
| Endotoxin: | < 10 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
