CCL28 is a novel chemokine that has the closest homology to CCL27/CTACK. CCL28 promotes chemotaxis of resting CD4, CD8 T-cells, and eosinophils. It binds to CCR3 and CCR10, causing calcium release in a dose-dependent manner. CCR10 (GPR2 orphan receptor) is also the target of CCL27/CTACK. CCL28 is mostly expressed by epithelial cells in a variety of tissues, with the highest level of expression seen in the normal and diseased colon. CCL28 is expressed in both normal and asthmatic lung tissues. In their mature sequences, human and murine CCL28 have 83% identity. Human CCL28 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Recombinant Human CCL28 is produced by our E.coli expression system and the target gene encoding Ile20-Tyr127 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
12.49 kDa
AP Mol Mass:
15 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
