Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3; respectively. The three MCP proteins are all chemoattractants for monocytes. CCL8 is chemotactic for and activates a variety of immune cells, including mast cells, eosinophils, and basophils; all of which are involved in the allergic response; monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 binds to several cell surface receptors, including CCR1; CCR2B and CCR5. Human CCL8/MCP-2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Recombinant Human CCL8 is produced by our E.coli expression system and the target gene encoding Gln24-Pro99 is expressed.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
8.9 kDa
AP Mol Mass:
12 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
