B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 is a disulfide-linked homodimer composed of one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD5/CD72 interacts with PTPN6/SHP-1, which promotes B-cell proliferation and differentiation. CD72 binds to CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and suppresses BCR signalling through interactions with the phosphatase SHP-1. Human CD72/Lyb-2 Recombinant Protein (Trx&His) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CD72/Lyb-2 Recombinant Protein (Trx&His) (RPES3362)
Product Code:
RPES3362
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
B-Cell Differentiation Antigen CD72, Lyb-2, CD72
Accession:
P21854
Sequence:
Arg117-Cys226
Fusion tag:
N-Trx
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human B-Cell Differentiation Antigen CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
30.6 kDa
AP Mol Mass:
14&17&32 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
