CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT); a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
Product Name:
Human CTGF/CCN2 Recombinant Protein (RPES0970)
Product Code:
RPES0970
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Connective tissue growth factor,CCN family member 2,Hypertrophic chondrocyte-specific protein 24,Insulin-like growth factor-binding protein 8,CTGF,IGFBP8
Accession:
P29279
Sequence:
Gln27-Ala349
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Gln27-Ala349 is expressed with a Fc tag at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
62.6 kDa
AP Mol Mass:
88 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
