Description
Recombinant Human Cyclophilin B/PPIase B/PPIB Protein
The Recombinant Human Cyclophilin B/PPIase B/PPIB Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Cyclophilin B/PPIase B/PPIB function and its implications in health and disease.
This product (SKU: RPCB1368) is produced using HEK293 cells and features a C-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 20.9 kDa with an observed molecular weight of 21 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography | |
Mammalian & Bacterial Expression Systems | |
High lot-to-lot consistency via strict QC |
Product Name: | Recombinant Human Cyclophilin B/PPIase B/PPIB Protein |
SKU: | RPCB1368 |
Size: | 10 μg |
Reactivity: | Human |
Synonyms: | CYP-S1, CYPB, HEL-S-39, OI9, SCYLP, PPIB, CYP-S1, peptidylprolyl isomerase B, CYPB, HEL-S-39, OI9, SCYLP |
Tag: | C-His |
Expression Host: | HEK293 cells |
Calculated MW: | 20.9 kDa |
Observed MW: | 21 kDa |
Gene ID: | 5479 |
Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human Cyclophilin B/PPIase B/PPIB Protein (RPCB1368), tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
Endotoxin: | < 1 EU/μg of the protein by LAL method. |
Purity: | ≥ 95 % as determined by SDS-PAGE. |
Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.Contact us for customized product form or formulation. |
Reconstitution: | Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Cyclophilin B (SCYLP, CyPB and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, Cyclophilin B mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization, and facilitating the activity of additional chaperones.