DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.
Product Name:
Human DCBLD2/ESDN Recombinant Protein (RPES4543)
Product Code:
RPES4543
Size:
100 µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
Discoidin, CUB and LCCL domain-containing protein 2,DCBLD2,CUB, LCCL and coagulation factor V/VIII-homology domains protein 1,Endothelial and smooth muscle cell-derived neuropilin-like protein,DCBLD2,CLCP1, ESDN
Accession:
NP_563615.3
Sequence:
Met 1-Ala482
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human DCBLD2 (NP_563615.3) (Met1-Ala482) was expressed with a polyhistidine tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
52.6 kDa
AP Mol Mass:
69-89 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
