Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Product Name:
Human ERP44 Recombinant Protein (RPES3182)
Product Code:
RPES3182
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Thioredoxin domain-containing protein 4, ER protein 44, KIAA0573, TXNDC4
Accession:
Q9BS26
Sequence:
Glu30-Asp402
Fusion tag:
C-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human ER resident protein 44 is produced by our Mammalian expression system and the target gene encoding Glu30-Asp402 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
44.2 kDa
AP Mol Mass:
50 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris HCl,10% Glycerol, pH7.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
