ERP72; also known as PDIA4; is an endoplasmic reticulum luminal protein which belongs to the protein disulfide isomerase family. ERP72 is a stress protein and participates in the catalysis of protein-S-S-bond rearrangement. Both of PDIA4 and PDIA3 function as proteases; protein disulfide isomerases; phospholipases or an arrangement of these. ERP72 compose part of a large chaperone multiprotein complex comprising CABP1; DNAJB11; HSP90B1; HSPA5; HYOU; PDIA2; PDIA4; PPIB; SDF2L1; UGT1A1 and very small amounts of ERP29; but not; or at very low levels; CALR nor CANX.
Product Name:
Human ERP72/PDIA4 Recombinant Protein (RPES4016)
Product Code:
RPES4016
Size:
100 µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
Protein Disulfide-Isomerase A4, Endoplasmic Reticulum Resident Protein 70, ER Protein 70, ERp70, Endoplasmic Reticulum Resident Protein 72, ER Protein 72, ERp-72, ERp72, PDIA4, ERP70, ERP72
Accession:
P13667
Sequence:
Met 1-Thr641
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the human PDIA4 (P13667) (Met1-Thr641) was expressed; fused with the Fc region of human IgG1 at the C-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
97.2 kDa
AP Mol Mass:
96 kDa
Formulation:
Lyophilized from sterile PBS; pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
