Recombinant Human Ferritin heavy chain/FTH1 Protein
The Recombinant Human Ferritin heavy chain/FTH1 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating Ferritin heavy chain/FTH1 function and its implications in health and disease.
This product (SKU: RPCB0755) is produced using E. coli and features a No tag tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 21.22 kDa with an observed molecular weight of 20-25 kDa under denaturing conditions, achieving ≥ 95 % as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
High Purity by Affinity Chromatography
Mammalian & Bacterial Expression Systems
High lot-to-lot consistency via strict QC
Product Name:
Recombinant Human Ferritin heavy chain/FTH1 Protein
High quality, high purity and low endotoxin recombinant Recombinant Human Ferritin heavy chain/FTH1 Protein (RPCB0755), tested reactivity in E. coli and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:
< 1 EU/μg of the protein by LAL method.
Purity:
≥ 95 % as determined by SDS-PAGE.
Formulation:
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.Contact us for customized product form or formulation.
Reconstitution:
Centrifuge the tube before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Storage:
Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Ferritin heavy polypeptide 1(FTH1), is a ubiquitous intracellular protein which stores iron in a soluble, non-toxic, readily available form. FTH1 has ferroxidase activity and is important for iron homeostasis. Iron is takenup in the ferrous form and deposited as ferric hydroxides after oxidation. Ferritin is composed of 24 subunits ofthe light and heavy ferritin chains. It plays a role in delivery of iron to cells and mediates iron uptake in capsulecells of the developing kidney. Variation of ferritin subunit composition may affect iron absorption and releasein different tissues. Deficiency of ferritin proteins may cause several neurodegenerative diseases. Almost allliving organisms can produce this protein, including algae, bacteria, higher plants, and animals.
Recombinant Human Ferritin heavy chain/FTH1 Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.
