Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Many members of this family have mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue healing, tumor growth, and invasion. FGF17 is an important molecule in the development of embryonic brains, and it serves as a signaling factor in the formation and patterning of the brain. FGF17 promotes cell proliferation and activation in cells that express FGF receptors. Human FGF7 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human FGF7 Recombinant Protein (RPES3866)
Product Code:
RPES3866
Size:
20 µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Fibroblast Growth Factor 17, FGF-17, FGF17
Accession:
O60258
Sequence:
Thr 23-Thr 216
Fusion tag:
Activity:
Measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 134 ng/ml.
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Fibroblast Growth Factor 17 is produced by our E.coli expression system and the target gene encoding Thr23-Thr216 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
22.6 kDa
AP Mol Mass:
22 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
