Description
| Product Name: | Recombinant Human GASP-1/WFIKKNRP Protein (His Tag) |
| SKU: | RPES8354 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | Human |
| Expression Host: | Mammalian |
| Accession: | Q8TEU8 |
| Sequence: | Leu35-His576 |
| Calculated Molecular Weight: | 59.5 kDa |
| Observed Molecular Weight: | 80 kDa |
| Synonyms: | UNQ, GASP, Wfikkn, GASP1, WFIKKNRP, WFIKKN2, UNQ9235, PRO31996, GASP-1, hGASP-1, WFDC20B |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
WAP , kazal , immunoglobulin , kunitz and NTR domain-containing protein 2 , also known as Growth and differentiation factor-associated serum protein 1 , WAP , follistatin , immunoglobulin , kunitz and NTR domain-containing-related protein , WFIKKN-related protein , WFIKKN2 and GASP1 , is a secreted protein that belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains , one Ig-like C2-type (immunoglobulin-like) domain , one Kazal-like domain , one NTR domain and one WAP domain. WFIKKN2 is primarily expressed in ovary , testis and brain , but not in liver. In fetal tissues , it is primarily expressed in brain , skeletal muscle , thymus and kidney. WFIKKN2 is a protease-inhibitor that contains multiple distinct protease inhibitor domains. It probably has serine protease-and metalloprotease-inhibitor activity. It inhibits the biological activity of mature myostatin , but not activin. WFIKKN2 protein binds mature GDF8/myostatin and myostatin propeptide and inhibits the biological activity of myostatin.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
